Vascular Endothelial Growth Factor (VEGF) Concentration Is Underestimated by Enzyme-Linked Immunosorbent Assay in the Presence of Anti-VEGF Drugs
Author(s) -
Hidenori Takahashi,
Yoko Nomura,
Junko Nishida,
Yujiro Fujino,
Yasuo Yanagi,
Hidetoshi Kawashima
Publication year - 2016
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.15-18245
Subject(s) - vegf receptors , vascular endothelial growth factor , enzyme , vascular endothelial growth factor a , medicine , vascular endothelial growth factor c , chemistry , endocrinology , biochemistry
Commercially available enzyme-linked immunosorbent assay (ELISA) kits are often used to monitor vascular endothelial growth factor (VEGF) levels in exudative age-related macular degeneration. To test their accuracy, this study performed measurements using the ELISA kits in the presence of anti-VEGF drugs.
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