PDGF-BB Enhances the Proliferation of Cells in Human Orbital Fibroblasts by Suppressing PDCD4 Expression Via Up-Regulation of microRNA-21
Author(s) -
Yoon Suk Lee,
Mihee Yun,
Jisun Paik,
SeongBeom Lee,
SukWoo Yang
Publication year - 2016
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.15-18157
Subject(s) - platelet derived growth factor receptor , transfection , cell growth , microrna , microbiology and biotechnology , platelet derived growth factor , small interfering rna , cell , growth factor , chemistry , cell culture , fibroblast , cancer research , biology , receptor , gene , biochemistry , genetics
The aim of this study was to investigate the effect of platelet-derived growth factor (PDGF)-BB on the proliferation of cells and its possible mechanism in human orbital fibroblasts.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom