Intervisit Repeatability of Retinal Blood Oximetry and Total Retinal Blood Flow Under Varying Systemic Blood Gas Oxygen Saturations | Zendy

Kalpana Rose | Zendy; Susith Kulasekara | Zendy; Christopher Hudson | Zendy

Open Access

Intervisit Repeatability of Retinal Blood Oximetry and Total Retinal Blood Flow Under Varying Systemic Blood Gas Oxygen Saturations

Author(s) -

Kalpana Rose,

Susith Kulasekara,

Christopher Hudson

Publication year - 2016

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.15-17908

Subject(s) - repeatability , retinal , hyperoxia , blood flow , medicine , blood pressure , oxygen saturation , retinal artery , arterial blood , anesthesia , ophthalmology , oxygen , chemistry , chromatography , organic chemistry , lung

The aim of the study is to validate and calibrate the Doppler spectral-domain optical coherence tomography (SD-OCT) derived total retinal blood flow (TRBF) and metabolic hyperspectral retinal camera (MHRC) derived oxygen saturation (SO2) of major retinal vessels in human volunteers using a novel and exact provocation technique (RespirAct) that allows the precise control of the end-tidal partial pressure of oxygen (PETO2). Between visit repeatability of the TRBF and retinal blood SO2 also were studied.

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