APR-246/PRIMA-1MetInhibits and Reverses Squamous Metaplasia in Human Conjunctival Epithelium | Zendy

Jing Li | Zendy; Cheng Li | Zendy; Guoliang Wang | Zendy; Zhen Liu | Zendy; Pei Chen | Zendy; Qichen Yang | Zendy; Nuo Dong | Zendy; Huping Wu | Zendy; Zuguo Liu | Zendy; Wei Li | Zendy

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APR-246/PRIMA-1^MetInhibits and Reverses Squamous Metaplasia in Human Conjunctival Epithelium

Author(s) -

Jing Li,

Cheng Li,

Guoliang Wang,

Zhen Liu,

Pei Chen,

Qichen Yang,

Nuo Dong,

Huping Wu,

Zuguo Liu,

Wei Li

Publication year - 2016

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.15-17519

Subject(s) - squamous metaplasia , epithelium , pathology , cytokeratin , metaplasia , immunostaining , ex vivo , staining , immunohistochemistry , goblet cell , conjunctiva , biology , medicine , in vivo , microbiology and biotechnology

Squamous metaplasia is a common pathologic condition in ocular surface diseases for which there is no therapeutic medication in clinic. In this study, we investigated the effect of a small molecule, APR-246/PRIMA-1(Met), on squamous metaplasia in human conjunctival epithelium.

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