Open AccessEssential Role for Pbx1 in Corneal Morphogenesis
Author(s) -
Mark Murphy,
Bozena Polok,
Daniel F. Schorderet,
Michael L. Cleary
Publication year - 2010
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.08-3327
Subject(s) - corneal epithelium , biology , stromal cell , cornea , morphogenesis , microbiology and biotechnology , epithelium , homeobox , cellular differentiation , transcription factor , genetics , gene , cancer research , neuroscience
The Pbx TALE (three-amino-acid loop extension) homeodomain proteins interact with class 1 Hox proteins, which are master regulators of cell fate decisions. This study was performed to elucidate the role of the Pbx1 TALE protein in the corneal epithelium of mice.