Open AccessPersistent Latent Tuberculosis Reactivation Risk in United States Immigrants
Author(s) -
Nicholas D. Walter,
John A. Painter,
Matthew Parker,
Phillip Lowenthal,
Jennifer Flood,
Yunxin Fu,
Redentor Asis,
Randall Reves
Publication year - 2014
Publication title -
american journal of respiratory and critical care medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.272
H-Index - 374
eISSN - 1535-4970
pISSN - 1073-449X
DOI - 10.1164/rccm.201308-1480oc
Subject(s) - medicine , tuberculosis , latent tuberculosis , cohort , chest radiograph , immigration , active tuberculosis , cohort study , demography , pediatrics , mycobacterium tuberculosis , surgery , pathology , radiography , archaeology , history , sociology
Current guidelines limit latent tuberculosis infection (LTBI) evaluation to persons in the United States less than or equal to 5 years based on the assumption that high TB rates among recent entrants are attributable to high LTBI reactivation risk, which declines over time. We hypothesized that high postarrival TB rates may instead be caused by imported active TB.