Open AccessExternal Validation of Risk Scores for Major Bleeding in a Population-Based Cohort of Transient Ischemic Attack and Ischemic Stroke Patients
Author(s) -
Nina A. Hilkens,
Linxin Li,
Peter M. Rothwell,
Ale Algra,
Jacoba P. Greving
Publication year - 2018
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.117.019259
Subject(s) - medicine , bleed , stroke (engine) , confidence interval , cohort , population , framingham risk score , statistic , surgery , disease , statistics , mechanical engineering , environmental health , engineering , mathematics
The S 2 TOP-BLEED score may help to identify patients at high risk of bleeding on antiplatelet drugs after a transient ischemic attack or ischemic stroke. The score was derived on trial populations, and its performance in a real-world setting is unknown. We aimed to externally validate the S 2 TOP-BLEED score for major bleeding in a population-based cohort and to compare its performance with other risk scores for bleeding.