Open AccessTxA 2 Receptor‐Based Vaccination: A Novel Potential Therapeutic Approach to Limit Thrombosis
Author(s) -
Ahmad Firdos
Publication year - 2018
Publication title -
journal of the american heart association
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.494
H-Index - 85
ISSN - 2047-9980
DOI - 10.1161/jaha.118.009861
Subject(s) - medicine , thrombosis , limit (mathematics) , vaccination , intensive care medicine , cardiology , immunology , mathematical analysis , mathematics
Aberrant intravascular platelet activation leads to thrombosis, which is the most common cause of ischemic heart attack and stroke. At the site of vascular injury, platelet activation and aggregation lead to the first wave of thrombin, a potent platelet activator, generation which helps in thrombus