Open AccessUpward Shift and Steepening of the Blood Pressure Response to Exercise in Hypertensive Subjects at High Altitude
Author(s) -
Caravita Sergio,
Faini Andrea,
Baratto Claudia,
Bilo Grzegorz,
Macarlupu Josè Luis,
Lang Morin,
Revera Miriam,
Lombardi Carolina,
Villafuerte Francisco C.,
Agostoni Piergiuseppe,
Parati Gianfranco
Publication year - 2018
Publication title -
journal of the american heart association
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.494
H-Index - 85
ISSN - 2047-9980
DOI - 10.1161/jaha.117.008506
Subject(s) - blood pressure , medicine , nifedipine , telmisartan , effects of high altitude on humans , hypoxia (environmental) , cardiology , calcium channel blocker , placebo , heart rate , aerobic exercise , endocrinology , oxygen , calcium , chemistry , alternative medicine , organic chemistry , pathology , anatomy
Acute exposure to high-altitude hypobaric hypoxia induces a blood pressure rise in hypertensive humans, both at rest and during exercise. It is unclear whether this phenomenon reflects specific blood pressure hyperreactivity or rather an upward shift of blood pressure levels. We aimed at evaluating the extent and rate of blood pressure rise during exercise in hypertensive subjects acutely exposed to high altitude, and how these alterations can be counterbalanced by antihypertensive treatment.