Open AccessArachidonic Acid, but Not Omega‐3 Index, Relates to the Prevalence and Progression of Abdominal Aortic Aneurysm in a Population‐Based Study of Danish Men
Author(s) -
Lindholt Jes S.,
Kristensen Katrine L.,
Burillo Elena,
MartinezLopez Diego,
Calvo Carlos,
Ros Emilio,
MartínVentura Jose L.,
SalaVila Aleix
Publication year - 2018
Publication title -
journal of the american heart association
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.494
H-Index - 85
ISSN - 2047-9980
DOI - 10.1161/jaha.117.007790
Subject(s) - medicine , abdominal aortic aneurysm , danish , cardiology , aortic aneurysm , population , aneurysm , surgery , aorta , environmental health , linguistics , philosophy
Animal models support dietary omega-3 fatty acids protection against abdominal aortic aneurysm (AAA), but clinical data are scarce. The sum of red blood cell proportions of the omega-3 eicosapentaenoic and docosahexaenoic acids, known as omega-3 index, is a valid surrogate for long-term omega-3 intake. We investigated the association between the omega-3 index and the prevalence and progression of AAA. We also investigated associations between AAA and arachidonic acid, an omega-6 fatty acid that is a substrate for proinflammatory lipid mediators.