Open AccessResidual Risk of Atherosclerotic Cardiovascular Events in Relation to Reductions in Very‐Low‐Density Lipoproteins
Author(s) -
Lawler Patrick R.,
Akinkuolie Akintunde O.,
Harada Paulo,
Glynn Robert J.,
Chasman Daniel I.,
Ridker Paul M,
Mora Samia
Publication year - 2017
Publication title -
journal of the american heart association
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.494
H-Index - 85
ISSN - 2047-9980
DOI - 10.1161/jaha.117.007402
Subject(s) - very low density lipoprotein , medicine , endocrinology , cholesterol , lipoprotein , triglyceride , statin , residual risk , lipoprotein particle
It is uncertain whether pharmacological reductions in very-low-density lipoproteins (VLDLs), and their component triglyceride and cholesterol could reduce residual risk of atherosclerotic cardiovascular disease (ASCVD) events among individuals in whom low-density lipoprotein cholesterol (LDL-C) has been adequately lowered. We examined whether individuals with greater on-statin reductions in VLDL-related measures-beyond reductions in LDL-C-were at further reduced risk of ASCVD.