English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Zendy Open

Presents the pdf analysis as premium feature

PDF Analysis

Insights

Presents the summarisation as premium feature

Summarisation

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the zaia usage as premium feature

ZAIA

Zendy Tools

Zendy Plus

Presents the access of premium content as premium feature

Premium Content

Background  Epicardial adipose tissue ( EAT ) is known to play an important role in atrial fibrillation substrate remodeling; however, the influence of sex on the association between  EAT  and left atrial ( LA ) transport function has not been elucidated.    Methods and Results  Of the 514 patients who underwent an index atrial fibrillation ablation procedure, 123 postmenopausal women with no history of hormone replacement therapy and 123 men who were matched for age, body mass index, type of atrial fibrillation, and  CHADS  2  score were enrolled. Before the procedure,  LA  volume,  LA  emptying fraction, and  EAT  volume were assessed using multislice computed tomography. Blood samples were obtained from a coronary sinus for analysis of serum adiponectin level before the ablation procedure. There were no differences in baseline demographics and laboratory findings between sexes. Compared with men, women had significantly less total  EAT  ( P <0.001) and higher serum adiponectin levels ( P =0.022) but higher proportions of periatrial  EAT  to total  EAT  volume (P/T  EAT  ratio,  P <0.001), lower  LA  emptying fraction ( P =0.042), and lower  LA  voltage ( P =0.034). The ratio of periatrial to total  EAT  volume correlated significantly with  LA  emptying fraction and  LA  voltage in both sexes, whereas total  EAT  volume and serum adiponectin level did not. On multivariate analysis, increased  LA  volume and higher periatrial:total  EAT  volume ratio were independent predictors of decreased  LA  emptying fraction in both sexes.    Conclusions  Compared with matched men, postmenopausal women with atrial fibrillation had higher periatrial adiposity, which was independently correlated with decreased  LA  voltage and  LA  transport function.

journal of the american heart association

Influence of Sex on the Association Between Epicardial Adipose Tissue and Left Atrial Transport Function in Patients With Atrial Fibrillation: A Multislice Computed Tomography Study