Open AccessGrowth Differentiation Factor 15 at 1 Month After an Acute Coronary Syndrome Is Associated With Increased Risk of Major Bleeding
Author(s) -
Lindholm Daniel,
Hagström Emil,
James Stefan K.,
Becker Richard C.,
Can Christopher P.,
Himmelmann Anders,
Katus Hugo A.,
Maurer Gerald,
LópezSendón José Luis,
Steg Philippe Gabriel,
Storey Robert F.,
Siegbahn Agneta,
Wallentin Lars
Publication year - 2017
Publication title -
journal of the american heart association
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.494
H-Index - 85
ISSN - 2047-9980
DOI - 10.1161/jaha.117.005580
Subject(s) - medicine , gdf15 , hazard ratio , acute coronary syndrome , proportional hazards model , risk factor , cardiology , surgery , myocardial infarction , confidence interval
Growth differentiation factor-15 (GDF-15) is related to major bleeding when measured at initial presentation in patients with acute coronary syndromes (ACSs) treated with dual antiplatelet therapy. It is unknown whether follow-up measurements provide additional information. The objective of this study was to investigate whether GDF-15 measured 1 month after an ACS provides additional information beyond the baseline levels with regard to the risk of major bleeding.