English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Zendy Open

Presents the pdf analysis as premium feature

PDF Analysis

Insights

Presents the summarisation as premium feature

Summarisation

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the zaia usage as premium feature

ZAIA

Zendy Tools

Zendy Plus

Presents the access of premium content as premium feature

Premium Content

Background  The association between obesity and mortality risks following coronary revascularization is not clear. We examined the associations of BMI (kg/m 2 ) with short‐, intermediate‐, and long‐term mortality following coronary artery bypass graft surgery ( CABG ) and percutaneous coronary intervention ( PCI ) in patients with different coronary anatomy risks and diabetes mellitus status.    Methods and Results  Data from the Alberta Provincial Project for Outcomes Assessment in Coronary Heart Disease (APPROACH) registry were analyzed. Using normal  BMI  (18.5–24.9) as a reference, multivariable‐adjusted hazard ratios for all‐cause mortality within 6 months, 1 year, 5 years, and 10 years were individually calculated for  CABG  and  PCI  with 4 prespecified  BMI  categories: overweight (25.0–29.9), obese class I (30.0–34.9), obese class  II  (35.0–39.9), and obese class  III  (≥40.0). The analyses were repeated after stratifying for coronary risks and diabetes mellitus status. The cohorts included 7560 and 30 258 patients for  CABG  and  PCI , respectively. Following  PCI , overall mortality was lower in patients with overweight and obese class I compared to those with normal  BMI ; however, 5‐ and 10‐year mortality rates were significantly higher in patients with obese class  III  with high‐risk coronary anatomy, which was primarily driven by higher mortality rates in patients without diabetes mellitus (5‐year adjusted hazard ratio, 1.78 [95%  CI , 1.11–2.85] and 10‐year adjusted hazard ratio, 1.57 [95% CI, 1.02–2.43]). Following  CABG , overweight was associated with lower mortality risks compared with normal  BMI .    Conclusions  Overweight was associated with lower mortality following  CABG  and  PCI . Greater long‐term mortality in patients with obese class  III  following  PCI , especially in those with high‐risk coronary anatomy without diabetes mellitus, warrants further investigation.

Differences in Short‐ and Long‐Term Mortality Associated With BMI Following Coronary Revascularization