Open AccessParticulate Matter and Hospital Admissions for Stroke in Beijing, China: Modification Effects by Ambient Temperature
Author(s) -
Huang Fangfang,
Luo Yanxia,
Guo Yuming,
Tao Lixin,
Xu Qin,
Wang Chao,
Wang Anxin,
Li Xia,
Guo Jin,
Yan Aoshuang,
Guo Xiuhua
Publication year - 2016
Publication title -
journal of the american heart association
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.494
H-Index - 85
ISSN - 2047-9980
DOI - 10.1161/jaha.116.003437
Subject(s) - medicine , stroke (engine) , odds ratio , ischemic stroke , ischemia , engineering , mechanical engineering
Background The impact of particulate matter (PM) on stroke may vary by particle size, stroke subtype, and patient characteristics and temperature. We examined the association of stroke admissions with PM in different subgroups in Beijing, China, during 2013–2014. Methods and Results A time‐stratified case‐crossover design was used to assess the relation between PM of different particle sizes and hospital admissions for ischemic and hemorrhagic stroke. Stratified analyses were performed by age, sex, and temperature. In total, there were 147 624 stroke admissions during the study period. In the whole‐period analysis, both PM 2.5 and PM 10 were positively associated with ischemic stroke admissions on the day of hospital admission and negatively associated with ischemic stroke at lag2 and lag3 day. In warm days (>13.5°C), the odds ratios of ischemic stroke admissions were 2.071 (95% CI 1.959–2.190), 1.470 (95% CI 1.391–1.554), and 1.590 (95% CI 1.493–1.694) per IQR increase in the same‐day PM 2.5 (82.0 μg/m 3 ), PM 2.5–10 (36.6 μg/m 3 ), and PM 10 (93.5 μg/m 3 ), respectively. For hemorrhagic stroke, the corresponding values were 1.941 (95% CI 1.658–2.273), 1.590 (95% CI 1.366–1.851), and 1.527 (95% CI 1.278–1.826). The positive associations were also observed in the other lag structures and were higher than in cold days (≤13.5°C). Conclusions This study suggests that the associations of PM 2.5 , PM 2.5–10 , and PM 10 with stroke admissions differed across levels of temperature. Short‐term exposure to PM 2.5 , PM 2.5–10 , and PM 10 was positively associated with hospital admissions for ischemic and hemorrhagic stroke on warm days (>13.5°C).