Open AccessIs There a Role for Colchicine in Acute Coronary Syndromes?
Author(s) -
Nidorf Stefan M.,
Verma Subodh
Publication year - 2015
Publication title -
journal of the american heart association
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.494
H-Index - 85
ISSN - 2047-9980
DOI - 10.1161/jaha.115.002372
Subject(s) - medicine , colchicine , coronary sinus , acute coronary syndrome , tolerability , cardiology , inflammasome , myocardial infarction , adverse effect , inflammation
In this issue of the Journal of the American Heart Association (JAHA) , Martinez et al[1][1] demonstrate for the first time in man, that the crystal‐induced NLRP3 inflammasome is activated within clinically stable coronary atherosclerotic plaque as evidenced by increased levels of IL‐1s and IL