Open AccessCerebral Oximetry as a Real‐Time Monitoring Tool to Assess Quality of In‐Hospital Cardiopulmonary Resuscitation and Post Cardiac Arrest Care
Author(s) -
Ibrahim Akram W.,
Trammell Antoine R.,
Austin Harland,
Barbour Kenya,
Onuorah Emeka,
House Dorothy,
Miller Heather L.,
Tutt Chandila,
Combs Deborah,
Phillips Roger,
Dickert Neal W.,
Zafari A. Maziar
Publication year - 2015
Publication title -
journal of the american heart association
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.494
H-Index - 85
ISSN - 2047-9980
DOI - 10.1161/jaha.115.001859
Subject(s) - medicine , resuscitation , cardiopulmonary resuscitation , return of spontaneous circulation , anesthesia , clinical death , emergency medicine
Background Regional cerebral oxygen saturation ( rSO 2 ) as assessed by near infrared frontal cerebral spectroscopy decreases in circulatory arrest and increases with high‐quality cardiopulmonary resuscitation. We hypothesized that higher rSO 2 during cardiopulmonary resuscitation and after return of spontaneous circulation ( ROSC ) would predict survival to discharge and neurological recovery. Methods and Results This prospective case series included patients experiencing in‐hospital cardiac arrest. Cerebral oximetry was recorded continuously from initiation of resuscitation until ROSC and up to 48 hours post‐arrest. Relationships between oximetry data during these time periods and outcomes of resuscitation survival and survival to discharge were analyzed. The cohort included 27 patients. Nineteen (70.3%) achieved ROSC , and 8 (29.6%) survived to discharge. Median arrest duration was 20.8 minutes (range=8 to 74). There was a significant difference in rSO 2 between resuscitation survivors and resuscitation nonsurvivors at initiation of the resuscitative efforts (35% versus 17.5%, P =0.03) and during resuscitation (36% versus 15%, P =0.0008). No significant association was observed between rSO 2 at ROSC or during the post‐arrest period and survival to discharge. Among patients who survived to discharge, there was no association between cerebral performance category and rSO 2 at ROSC , during resuscitation, or post‐arrest. Conclusions Higher rSO 2 levels at initiation of resuscitation and during resuscitation are associated with resuscitation survival and may reflect high‐quality cardiopulmonary resuscitation. However, in this small series, rSO 2 was not predictive of good neurological outcome. Larger studies are needed to determine whether this monitoring modality can be used to improve clinical outcomes.