Open AccessLp‐ PLA 2 , Plaque Inflammation and Lesion Development Vary Fundamentally Between Different Vascular Sites
Author(s) -
Marsche Gunther
Publication year - 2015
Publication title -
journal of the american heart association
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.494
H-Index - 85
ISSN - 2047-9980
DOI - 10.1161/jaha.115.001800
Subject(s) - medicine , inflammation , platelet activating factor , lesion , polyunsaturated fatty acid , lipid oxidation , pharmacology , pathology , biochemistry , fatty acid , chemistry , antioxidant
Lp‐PLA2 is also known as platelet activating factor (PAF) acetylhydrolase (PAF‐AH) or PLA2G7, owing to its hierarchical position in the PLA2 superfamily. Lp‐PLA2 or PAF‐AH was discovered based on its ability to catalyze the removal of the acetyl group at the sn‐2 position of the potent