Open AccessRole of Heme in Cardiovascular Physiology and Disease
Author(s) -
Sawicki Konrad Teodor,
Chang HsiangChun,
Ardehali Hossein
Publication year - 2015
Publication title -
journal of the american heart association
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.494
H-Index - 85
ISSN - 2047-9980
DOI - 10.1161/jaha.114.001138
Subject(s) - medicine , disease , physiology , heme , atherosclerotic cardiovascular disease , intensive care medicine , biochemistry , enzyme , chemistry
Heme is an essential molecule for living aerobic organisms and is involved in a remarkable array of diverse biological processes. In the cardiovascular system, heme plays a major role in gas exchange, mitochondrial energy production, antioxidant defense, and signal transduction. Although heme, as