Open AccessPlasma Phospholipid Fatty Acid Biomarkers of Dietary Fat Quality and Endogenous Metabolism Predict Coronary Heart Disease Risk: A Nested Case‐Control Study Within the Women's Health Initiative Observational Study
Author(s) -
Matthan Nirupa R.,
Ooi Esther M.,
Van Horn Linda,
Neuhouser Marian L.,
Woodman Richard,
Lichtenstein Alice H.
Publication year - 2014
Publication title -
journal of the american heart association
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.494
H-Index - 85
ISSN - 2047-9980
DOI - 10.1161/jaha.113.000764
Subject(s) - medicine , odds ratio , fatty acid , endocrinology , logistic regression , physiology , biochemistry , biology
Although the relationship between dietary fat quality and coronary heart disease (CHD) risk has been evaluated, typically using diet questionnaires, results are inconsistent and data in postmenopausal women are limited. Plasma phospholipid fatty acid (PL-FA) profiles, reflecting dietary intake and endogenous FA metabolism, may better predict diet-CHD risk.