Open AccessArginase II: Atherogenesis Beyond Enzyme Activity
Author(s) -
Pandey Deepesh,
Romer Lewis,
Berkowitz Dan E.
Publication year - 2013
Publication title -
journal of the american heart association
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.494
H-Index - 85
ISSN - 2047-9980
DOI - 10.1161/jaha.113.000392
Subject(s) - medicine , gerontology
It is now well established that endothelial cells (EC) and vascular smooth muscle cells (VSMC) are two specialized and interacting components of the vascular wall that orchestrate the pathogenesis of atherosclerosis through complex signaling cascades. Endothelial dysfunction is an early and critical