Open AccessFeeding Sugar to Tumors: With a Supplement of miR?
Author(s) -
BlancBrude Olivier P.,
Tedgui Alain
Publication year - 2012
Publication title -
journal of the american heart association
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.494
H-Index - 85
ISSN - 2047-9980
DOI - 10.1161/jaha.112.006213
Subject(s) - medicine , angiogenesis , regulator , nitric oxide , apoptosis , cancer research , microbiology and biotechnology , biochemistry , biology , gene
Thrombospondin-1 (TSP-1) is a 450-kDa adhesive glycoprotein that was initially discovered in platelets and subsequently in a variety of cell types. TSP-1 is one of the first physiological inhibitors of angiogenesis to be identified and remains one of the most potent and best described.[1][1] TSP-1