Cross-Ancestry Investigation of Venous Thromboembolism Genomic Predictors | Zendy

Florian Thibord | Zendy; Derek Klarin | Zendy; Jennifer A. Brody | Zendy; MingHuei Chen | Zendy; Michael G. Levin | Zendy; Daniel I. Chasman | Zendy; Ellen L. Goode | Zendy; Kristian Hveem | Zendy; Maris TederLaving | Zendy; Ángel Martínez-Pérez | Zendy; Dylan Aïssi | Zendy; Delphine Daian-Bacq | Zendy; Kaoru Ito | Zendy; Pradeep Natarajan | Zendy; Pamela L. Lutsey | Zendy; Girish N. Nadkarni | Zendy; Paul S. de Vries | Zendy; Gabriel Cuéllar-Partida | Zendy; Brooke N. Wolford | Zendy; Jack Pattee | Zendy; Charles Kooperberg | Zendy; Sigrid K. Brækkan | Zendy; Ruifang LiGao | Zendy; Noémie Saut | Zendy; Corriene Sept | Zendy; Marine Germain | Zendy; Renae Judy | Zendy; Kerri L. Wiggins | Zendy; Darae Ko | Zendy; Christopher J. O’Donnell | Zendy; Kent D. Taylor | Zendy; Franco Giulianini | Zendy; Mariza de Andrade | Zendy; Therese Haugdahl Nøst | Zendy; Anne Boland | Zendy; JeanPhilippe Empana | Zendy; Satoshi Koyama | Zendy; Thomas Gilliland | Zendy; Ron Do | Zendy; Jennifer E. Huffman | Zendy; Xin Wang | Zendy; Wei Zhou | Zendy; José Manuel Soria | Zendy; Juan Carlos Souto | Zendy; Nathan Pankratz | Zendy; Jeffery Haessler | Zendy; Kristian Hindberg | Zendy; Frits R. Rosendaal | Zendy; Constance Turman | Zendy; Robert Olaso | Zendy; Rachel L. Kember | Zendy; Traci M. Bartz | Zendy; Julie A. Lynch | Zendy; Susan R. Heckbert | Zendy; Sebastian M. Armasu | Zendy; Ben Brumpton | Zendy; David M. Smadja | Zendy; Xavier Jouven | Zendy; Issei Komuro | Zendy; Katharine Clapham | Zendy; Ruth J. F. Loos | Zendy; Cristen J. Willer | Zendy; Maria SabaterLleal | Zendy; James S. Pankow | Zendy; Alexander P. Reiner | Zendy; Vânia M. Morelli | Zendy; Paul M. Ridker | Zendy; Astrid van Hylckama Vlieg | Zendy; Jean-François Deleuze | Zendy; Peter Kraft | Zendy; Daniel J. Rader | Zendy; Kyung Min Lee | Zendy; Bruce M. Psaty | Zendy; Anne Heidi Skogholt | Zendy; Joseph Emmerich | Zendy; Pierre Suchon | Zendy; Stephen S. Rich | Zendy; Ha My T. Vy | Zendy; Weihong Tang | Zendy; Rebecca D. Jackson | Zendy; JohnBjarne Hansen | Zendy; PierreEmmanuel Morange | Zendy; Christopher Kabrhel | Zendy; DavidAlexandre Trégouët | Zendy; Scott M. Damrauer | Zendy; Andrew D. Johnson | Zendy; Nicholas L. Smith | Zendy

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Cross-Ancestry Investigation of Venous Thromboembolism Genomic Predictors

Author(s) -

Florian Thibord,

Derek Klarin,

Jennifer A. Brody,

MingHuei Chen,

Michael G. Levin,

Daniel I. Chasman,

Ellen L. Goode,

Kristian Hveem,

Maris TederLaving,

Ángel Martínez-Pérez,

Dylan Aïssi,

Delphine Daian-Bacq,

Kaoru Ito,

Pradeep Natarajan,

Pamela L. Lutsey,

Girish N. Nadkarni,

Paul S. de Vries,

Gabriel Cuéllar-Partida,

Brooke N. Wolford,

Jack Pattee,

Charles Kooperberg,

Sigrid K. Brækkan,

Ruifang LiGao,

Noémie Saut,

Corriene Sept,

Marine Germain,

Renae Judy,

Kerri L. Wiggins,

Darae Ko,

Christopher J. O’Donnell,

Kent D. Taylor,

Franco Giulianini,

Mariza de Andrade,

Therese Haugdahl Nøst,

Anne Boland,

JeanPhilippe Empana,

Satoshi Koyama,

Thomas Gilliland,

Ron Do,

Jennifer E. Huffman,

Xin Wang,

Wei Zhou,

José Manuel Soria,

Juan Carlos Souto,

Nathan Pankratz,

Jeffery Haessler,

Kristian Hindberg,

Frits R. Rosendaal,

Constance Turman,

Robert Olaso,

Rachel L. Kember,

Traci M. Bartz,

Julie A. Lynch,

Susan R. Heckbert,

Sebastian M. Armasu,

Ben Brumpton,

David M. Smadja,

Xavier Jouven,

Issei Komuro,

Katharine Clapham,

Ruth J. F. Loos,

Cristen J. Willer,

Maria SabaterLleal,

James S. Pankow,

Alexander P. Reiner,

Vânia M. Morelli,

Paul M. Ridker,

Astrid van Hylckama Vlieg,

Jean-François Deleuze,

Peter Kraft,

Daniel J. Rader,

Kyung Min Lee,

Bruce M. Psaty,

Anne Heidi Skogholt,

Joseph Emmerich,

Pierre Suchon,

Stephen S. Rich,

Ha My T. Vy,

Weihong Tang,

Rebecca D. Jackson,

JohnBjarne Hansen,

PierreEmmanuel Morange,

Christopher Kabrhel,

DavidAlexandre Trégouët,

Scott M. Damrauer,

Andrew D. Johnson,

Nicholas L. Smith

Publication year - 2022

Publication title -

circulation

Language(s) - Uncategorized

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.122.059675

Subject(s) - genome wide association study , medicine , genetic association , mendelian randomization , genetics , locus (genetics) , candidate gene , multiple comparisons problem , single nucleotide polymorphism , bioinformatics , biology , gene , genotype , genetic variants , mathematics , statistics

Venous thromboembolism (VTE) is a life-threatening vascular event with environmental and genetic determinants. Recent VTE genome-wide association studies (GWAS) meta-analyses involved nearly 30 000 VTE cases and identified up to 40 genetic loci associated with VTE risk, including loci not previously suspected to play a role in hemostasis. The aim of our research was to expand discovery of new genetic loci associated with VTE by using cross-ancestry genomic resources.

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