Open AccessNeuroimaging and motor development of twins with congenital microcephaly associated with Zika virus: a case report
Author(s) -
Tainã Ribeiro Klinger,
Luciana Sayuri Sanada,
Natália Alves Menegol,
Viviane de Rezende Santos Passos Lima,
Gabriela Santos de Melo,
Ellen Soares Guedes,
Karina Laurenti Sato
Publication year - 2021
Publication title -
acta fisiátrica
Language(s) - English
Resource type - Journals
eISSN - 2317-0190
pISSN - 0104-7795
DOI - 10.11606/issn.2317-0190.v28i3a181212
Subject(s) - microcephaly , zika virus , neuroimaging , medicine , pediatrics , lesion , motor function , physical medicine and rehabilitation , motor skill , pathology , virus , psychiatry , immunology
Objective: We aimed to describe a case of congenital microcephaly caused by Zika virus infection in a monozygotic twin pregnancy. Methods: Transfontanelle ultrasonography and cranial computed tomography revealed different lesion patterns for both twins with congenital microcephaly caused by Zika virus infection. Motor development assessments were performed using the Alberta Infant Motor Scale and the Gross and Motor Function Measure before, during, and after physiotherapy. Results: The evaluations showed differences in motor acquisition between the twins. The values in the first case were much lower than those in the second case, which showed more motor delay. Conclussion: The present study showed that despite the twins being monozygotic, the effects of neurological lesions as revealed by neuroimaging were worse in the first case, and even with two weekly rehabilitation sessions, motor development over time was considerably worse in the twin in case 1 than in the other twin.