Open AccessProstate cancer profiles and associated factors in Criciúma – Santa Catarina, Brazil
Author(s) -
Ives Alexandre Yutani Koseki,
Matheus Rosso Benedet,
Guilherme de Sá,
Rafael Conti,
R Bernardi,
André Rodrigues da Silva,
Daniel Izé Ronchi,
Kristian Madeira
Publication year - 2019
Publication title -
medicina
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.104
H-Index - 10
eISSN - 2176-7262
pISSN - 0076-6046
DOI - 10.11606/issn.2176-7262.v52i2p104-109
Subject(s) - rectal examination , medicine , odds ratio , prostate cancer , prostate , biopsy , prostate specific antigen , cancer , prostate biopsy , population , prostate cancer screening , gynecology , odds , urology , logistic regression , environmental health
Background: Prostate cancer is the second most incident of the male population in Brazil. The aim of this study is to analyze the frequency of risk factors associated to the evolution of the prostate cancer and the impact of conducting examinations in the age range (55-69 years old), in assisting health professionals to manage and prevent the disease. Methods: A case-control study was performed on patients from 2011 to 2016 in Criciúma – SC, Brazil. The sample was divided into two groups, one with biopsy for prostate adenocarcinoma (case; n = 124) and the other with a negative biopsy (control; n = 251). The following variables were compared between the two groups: age, family history of prostate cancer, prostate specific antigen, and altered digital rectal examination. Results: In the case group, ranging between 55-69 years old, there was a significant higher of altered digital rectal examination (p < 0.001, odds ratio 15.5 and positive predictive value 91.3%), prostate-specific antigen ≥ 4 ng/mL (p < 0.001, odds ratio 7.02 and positive predictive value 56.2%) and when both exams were altered (p < 0.001, odds ratio was 19.63 and the positive predictive value was 90.5%). Conclusion: This findings show that, mainly between 55-69 years old, there is a significant correlation between positive biopsy, altered digital rectal examination, and PSA ≥ 4 ng/mL.