Open AccessPostoperative evolution of insulin sensitivity in diabetic patients
Author(s) -
Rafael Gomes de Melo D'Elia,
Roberto de Cleva,
Filippe Camarotto,
Miller Barreto,
Iago Oliveira Ferradans,
Kleber Jessivaldo Gomes das Chagas,
Marco Aurélio Santo
Publication year - 2019
Publication title -
revista de medicina
Language(s) - English
Resource type - Journals
eISSN - 1679-9836
pISSN - 0034-8554
DOI - 10.11606/issn.1679-9836.v98isupplp3-3
Subject(s) - medicine , sleeve gastrectomy , insulin resistance , insulin , gastric bypass , cohort , retrospective cohort study , diabetes mellitus , surgery , significant difference , type 2 diabetes , obesity , endocrinology , weight loss
The purpose of this study was to compare postoperative evolution of insulin sensibility in diabetic patients after the two most relevant bariatric surgeries nowadays, Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG). A retrospective cohort study was conducted with type 2 diabetic patients, who underwent RYGB or SG from 2013 to 2018. The laboratory and anthropometric data was analyzed pre-surgery and during a 2-year follow-up. The tool chosen for this comparison was the HOMA2 nonlinear equations, calculated from fasting glycemia and blood insulin. The two surgical procedures were compared. There was significant difference between both evolutions in the first 6-months follow-up (p=0.029), but no difference was presented at the 1-year (p=0.053) or at the 2-year follow-up (p>0.05). Therefore, there was no long-term difference between surgeries, which fuels discussions about their mechanisms of action and their relevance in the treatment of insulin resistance.