Open Accessrole of prostaglandin F2α on ovulation and LH release in cows
Author(s) -
Natália Ávila de Castro,
C. E. P. Leonardi,
Jaswant Singh,
Augusto Schneider,
Paulo Bayard Dias Gonçalves,
Fernando Caetano de Oliveira,
Camila Amaral D’Ávila,
Rogério Ferreira,
Bernardo Garziera Gasperin,
Elizângela Mírian Moreira,
Jéssica de Souza Andrade,
Luiz Francisco Machado Pfeifer
Publication year - 2021
Publication title -
brazilian journal of veterinary research and animal science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.187
H-Index - 17
eISSN - 1678-4456
pISSN - 1413-9596
DOI - 10.11606/issn.1678-4456.bjvras.2021.175001
Subject(s) - ovulation , cloprostenol , follicular phase , prostaglandin , saline , medicine , endocrinology , follicle , prostaglandin f , induced ovulation , chemistry , andrology , hormone
This study aimed to evaluate the role of prostaglandin F2α (PGF) on ovulation. In Experiment 1, cows were randomly allocated to two treatments to receive 150 μg of d-Cloprostenol (PGF Group, n = 12) or 2 mL of NaCl 0.9% (Control Group, n = 11) and CIDRs, were removed 4 days later. No cow ovulated in Control and PGF groups. In Experiment 2, cows were randomly separated into two experimental groups to receive 4 injections of 150 μg of d-Cloprostenol (n = 9) or 2 mL of NaCL 0.9% (n = 9). In this experiment, ovulation was not observed in any cows. In Experiment 3, ovariectomized cows receive three injections of 300μg of PGF analog (PGF Group, n = 5), 100μg of Lecirelin (GnRH Group, n = 5) or 2 mL of PBS (Control Group, n = 4). The LH concentration was higher (P 11.5 mm) were treated with Saline (Control Group, n = 6); Lecirelin (GnRH Group, n = 7) or Cloprostenol Sodium (PGF Group, n = 6). There was a significant increase in the vascular area of follicles from 0 to 24 h in GnRH and PGF treatments. In conclusion, PGF was not able to induce ovulation in cows with high or low plasma progesterone concentration. Additionally, PGF alone was not able to induce LH release and follicle luteinization, but increased follicular vascularization.