Open AccessAntimicrobial resistance in bacteria isolated from pigs with respiratory clinical signs in Brazil
Author(s) -
Maysa Serpa Gonçalves,
Juliana Amália Fonte Bôa do Nascimento,
Mirian Fátima Alves,
Maria Isabel Maldonado Coelho Guedes,
Adrienny Trindade Reis,
Marcos Bryan Heinemann,
Andrey Pereira Lage,
Zélia Inês Portela Lobato,
Elaine Maria Seles Dorneles
Publication year - 2020
Publication title -
brazilian journal of veterinary research and animal science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.187
H-Index - 17
eISSN - 1678-4456
pISSN - 1413-9596
DOI - 10.11606/issn.1678-4456.bjvras.2020.160956
Subject(s) - microbiology and biotechnology , enrofloxacin , antimicrobial , trimethoprim , erythromycin , antibiotic resistance , biology , tetracycline , florfenicol , streptococcus suis , bordetella bronchiseptica , penicillin , sulfadiazine , oxytetracycline , ceftiofur , sulfamethoxazole , lincomycin , ciprofloxacin , antibiotics , bacteria , biochemistry , genetics , virulence , gene
Antimicrobial resistance is a current and important issue to public health, and it is usually associated with the indiscriminate use of antimicrobials in animal production. This study aimed to evaluate the antimicrobial susceptibility profile in bacterial isolates from pigs with clinical respiratory signs in Brazil. One hundred sixty bacterial strains isolated from pigs from 51 pig farms in Brazil were studied. In vitro disk-diffusion method was employed using 14 antimicrobial agents: amoxicillin, penicillin, ceftiofur, ciprofloxacin, enrofloxacin, chlortetracycline, doxycycline, oxytetracycline, tetracycline, erythromycin, tilmicosin, florfenicol, lincomycin, and sulfadiazine/trimethoprim. The majority of isolates were resistant to at least one antimicrobial agent (98.75%; 158/160), while 31.25% (50/160) of the strains were multidrug resistant. Streptococcus suis and Bordetella bronchiseptica were the pathogens that showed higher resistance levels. Haemophilus parasuis showed high resistance levels to sulfadiazine/trimethoprim (9/18=50%). We observed that isolates from the midwestern and southern regions exhibited four times greater chance of being multidrug resistant than the isolates from the southeastern region studied. Overall, the results of the present study showed a great level of resistance to lincomycin, erythromycin, sulfadiazine/trimethoprim, and tetracycline among bacterial respiratory pathogens isolated from pigs in Brazil. The high levels of antimicrobial resistance in swine respiratory bacterial pathogens highlight the need for the proper use of antimicrobials in Brazilian pig farms.