Open AccessIdentifying and quantifying the factors associated with cholera-related death during the 2018 outbreak in Nigeria
Author(s) -
Kelly Elimian,
Anwar Musah,
Chinwe Lucia Ochu,
Somtochukwu Stella Onwah,
Oyeronke Oyebanji,
Sebastian Yennan,
Ibrahima Socé Fall,
Michel K. Yao,
Caroline Martin,
Eme Ekeng,
Patrick Abok,
Linda Haj Omar,
Thieno Balde,
Adamu Kankia,
Nanpring Williams,
Kitgakka Mutbam,
Dhamari Naidoo,
Ifeanyi Okudo,
Wondimagegnehu Alemu,
Peter Clement,
Chikwe Ihekweazu
Publication year - 2020
Publication title -
the pan african medical journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.287
H-Index - 30
ISSN - 1937-8688
DOI - 10.11604/pamj.2020.37.368.20981
Subject(s) - cholera , medicine , context (archaeology) , outbreak , case fatality rate , logistic regression , environmental health , demography , odds ratio , psychological intervention , population , geography , virology , archaeology , psychiatry , sociology
cholera outbreaks in Nigeria are often associated with high case fatality rates; however, there is a dearth of evidence on context-specific factors associated with the trend. This study therefore aimed to identify and quantify the factors associated with cholera-related deaths in Nigeria. Methods using a cross-sectional design, we analysed surveillance data from all the States that reported cholera cases during the 2018 outbreak, and defined cholera-related death as death of an individual classified as having cholera according to the Nigeria Centre for Disease Control case definition. Factors associated with cholera-related death were assessed using multivariable logistic regression and findings presented as adjusted odds ratios (ORs) with 95% Confidence Intervals (95% CIs). Results between January 1 and November 19, 2018, 41,394 cholera cases were reported across 20 States, including 815 cholera-related deaths. In the adjusted multivariable model, older age, male gender, living in peri-urban areas or in flooded states, infection during the rainy season, and delay in seeking health care by >2 days were positively associated with cholera-related death; whereas living in urban areas, hospitalisation in the course of illness, and presentation to a secondary hospital were negatively associated with cholera-related death. Conclusion cholera-related deaths during the 2018 outbreak in Nigeria appeared to be driven by multiple factors, which further reemphasises the importance of adopting a multisectoral approach to the design and implementation of context-specific interventions in Nigeria.