Open AccessDisseminated and ulcerative basidiobolomycosis simulating a buruli ulcer in an immunocompetent girl in Southern Benin
Author(s) -
Akimath Habib,
Christelle D ́almeida,
Bérénice Dégboé,
Benjamin Morvant,
Marlène Lyne Ganlo,
Ambroise Adeye,
Anne Croué,
Gbètogo Maxime Kiki,
Espoir Sodjinou
Publication year - 2020
Publication title -
the pan african medical journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.287
H-Index - 30
ISSN - 1937-8688
DOI - 10.11604/pamj.2020.37.227.20994
Subject(s) - medicine , buruli ulcer , mycobacterium ulcerans , girl , nodule (geology) , abdomen , dermatology , zygomycosis , surgery , pathology , antifungal , disease , psychology , paleontology , developmental psychology , amphotericin b , biology
Basidiobolomycosis is a subcutaneous mycosis, for which non-specific clinical presentation can be a source of diagnostic wandering. A 5-year-old girl was brought for consultation with chronic ulcers of the pelvic limbs evolving for 8 months. The lesions started when the girl was 18 months old with a painless, pruritic nodule of the right buttock, indurated placard following progressive extension to the pelvic limbs, back and abdomen, and secondarily ulcerated in several places. On examination, there was an alteration of the general condition, a large, indurated and erythematous plaque, with sharp edges. On this plaque, there were nodular lesions and necrotic ulcers, with detached margins. The left knee was blocked in flexion. Ziehl staining and polymerase chain reaction for Mycobacterium ulcerans were negative. The histopathological picture was suggestive of basidiobolomycosis. The evolution was favorable after giving her ketoconazole (100mg per day) for 14 weeks associated with surgery and physiotherapy. This clinical case confirms the difficulties in diagnosing basidiobolomycosis, especially in endemic areas of Buruli ulcer.