
Дослідження стероїдних сполук у талабану польового екстракті густому (Thlaspiarvense L.)
Author(s) -
О. І. Панасенко,
G. S. Tartynska,
V. V. Hutsol
Publication year - 2018
Publication title -
medična ì klìnìčna himiâ
Language(s) - English
Resource type - Journals
eISSN - 2414-9934
pISSN - 2410-681X
DOI - 10.11603/mcch.2410-681x.2018.v0.i1.8868
Subject(s) - herb , stigmasterol , population , traditional medicine , antioxidant , medicine , biology , chemistry , pharmacology , medicinal herbs , chromatography , biochemistry , environmental health
. Environment, lowered physical activity and low standards of living lead to the increase of incidence of diseases in the population of Ukraine, in particular, pathologies of prostate in men. Creation of plant-derived medicines for the treatment of the abovementioned pathologies is of great interest nowadays. Phytomedicines possess low toxicity andare characterized by high safety level, absence of negative action towards sexual function, possibility of long-term usage in complex therapy. Phytoremedies with prostate protective activity usually include extracts of plants that show anti-inflammatory, immune stimulating, spasmolytic, diuretic, antioxidant, antitumor activity. Field pennycress belongs to the prospective sources of obtaining prostate protective remedies. Field pennycress (Thlaspiarvense L.) from cabbage family (Brassicaceae) shows the abovementioned types of activity, thus it is used for the prophylaxis and treatment of benign prostate hyperplasia. Among biologically active compounds of herbal medicines a certain role in reaching therapeutic effect play steroidal compounds, which show prostate protective, cytostatic activity. Thus, for a more detailed research on field pennycress herb its thick extract was obtained, in which the qualitative composition and quantitative content of steroidal compounds was studied.Research Methods. Gas chromatography was used for the phytosterols’ study in the thick extract of field pennycress herb.Results and Discussion. 3 compounds were identified using the gas chromatography method: stigmasterol, sitosterol and lanosta-9(11),24-diene-3-ol acetate and their quantitative content (0.12 mg/kg, 0.16 mg/kg, 0.29 mg/kgrespectively) was determined in the thick extract of field pennycress herb.Conclusions. The obtained results might be used at quality control methods development for the thick extract of field pennycress herb.