Дослідження органічних кислот у сировині амброзії полинолистої

Introduction. Organic acids are a prospective group of biologically active compounds of natural origin. Organic acids show anti-inflammatory, antioxidant, hepatoprotective, antimicrobial activity, as well as take part in metabolic processes and improve the state of intestinal microflora. The data on the organic acids of common ragweed are rather limited, thus the research upon this group of biologically active compounds in common ragweed plant material is of great current interest.The aim of the study – to learnthe organic acids in common ragweed plant material by the vegetation stages of the plant.Research Methods. The study of organic acids was carried out using gas chromatography in common ragweed leaves and roots, collected in the vegetation phase, beginning of flower-bud formation and fruiting phase.Results and Discussion. Citric (4769.3 mg/kg) and oxalic (2046.8 mg/kg) acids were found in the highest quantity in common ragweed leaves in the vegetation stage, in the roots – fumaric (2580.9 mg/kg) andcitric (782.3 mg/kg) acids. In the leaves at the beginning of flower-bud formation oxalic (1374.4 mg/kg) andcitric (813.0 mg/kg) acids prevailed, and in the roots at the same stage – citric (1705.1 mg/kg) andmalic (1399.5 mg/kg) acids. In the leaves pre-readied at the fruiting phase citric (2879.4 mg/kg) andoxalic (513.5 mg/kg) acids dominated. Such organic acids as fumaric (242.2 mg/kg) andmalic (186.7 mg/kg) prevailed in the roots at the fruiting phase.Conclusions. Organic acids in common ragweed leaves and roots, collected in the vegetation phase, beginning of flower-bud formation and fruiting phase, were studied using gas chromatography. Aliphatic carboxylic acids, in particular, citric, oxalic, malonic, fumaric and malic acids, quantitatively dominated in the plant material. The highest content of organic acids was determined in the leaves collected during the vegetation phase. The results obtained allow expecting antioxidant and antimicrobial activity of herbal medicines on the basis of common ragweed plant material.