Open AccessResearch of hepatoprotective melatonin properties and the role of polymorphism of the geme mtnr1b in patients with diabetes mellitus type 2
Author(s) -
О. М. Олещук,
Ya. I. Ivankiv,
O. A. Shumska
Publication year - 2017
Publication title -
medična ì klìnìčna himiâ
Language(s) - English
Resource type - Journals
eISSN - 2414-9934
pISSN - 2410-681X
DOI - 10.11603/mcch.2410-681x.2016.v0.i4.7256
Subject(s) - type 2 diabetes mellitus , melatonin , medicine , polymorphism (computer science) , diabetes mellitus , endocrinology , carbohydrate metabolism , gene polymorphism , biology , gene , biochemistry , genotype
The application of melatonin to improve the treatment of patients with diabetes mellitus (DM) type 2, including hepatoprotective properties and its effect on carbohydrate metabolism were studied. It is established the relationship between gene polymorphism MT2 receptor, namely its variants: rs1387153 and rs10830963 and levels of fasting glucose and type 2 diabetes.