Open AccessInfluences of stress on lipid peroxidation and antioxidant systems of the heart of male and female rats with different resistance to hypoxia
Author(s) -
Yu. M. Ordunskiy
Publication year - 2016
Publication title -
medična ì klìnìčna himiâ
Language(s) - English
Resource type - Journals
eISSN - 2414-9934
pISSN - 2410-681X
DOI - 10.11603/mcch.2410-681x.2016.v0.i3.6949
Subject(s) - lipid peroxidation , oxidative stress , hypoxia (environmental) , antioxidant , medicine , endocrinology , chemistry , oxygen , biochemistry , organic chemistry
We investigated the effect of chronic stress on changes in lipid peroxidation and antioxidant protection in high- and low resistant to hypoxia (HR and LR) rats of different sex. Chronic stress causes the development of oxidative and carbonyl stress in HR and LR animals, most in the LR. At the same time antioxidant protection was increased. More intensive lipid peroxidation was observed in males compared with females.