Open AccessFeatures of the damaging eff ect of chronic stress on rats’ heart of different sex
Author(s) -
I. R. Mits,
O. V. Denеfil
Publication year - 2016
Publication title -
medična ì klìnìčna himiâ
Language(s) - English
Resource type - Journals
eISSN - 2414-9934
pISSN - 2410-681X
DOI - 10.11603/mcch.2410-681x.2016.v0.i1.6277
Subject(s) - lipid peroxidation , endocrinology , medicine , chronic stress , potassium , sodium , oxidative stress , physiology , chemistry , organic chemistry
We investigated the effect of chronic prenatal, postnatal stress and their combination on changes in lipid peroxidation, Na+,K+-ATPase, AST and ALT, the morphological structure of the rats’ heart of different sex. It was revealed the increase in lipid peroxidation products, increase in the activity of sodium-potassium ATP ase in males and the imbalance of its work in females, an increase of ALT in males. Most increase of necrosis’ amount was observed at postnatal stress in the heart of the males, combined – in females.