Open AccessTHE INFLUENCE OF HEAVY METAL S, ORGANOPHOSPHATE PESTICIDES AND PEPTIDES ON THE ENZYME ACTIVITY OF GLUTATHIONE SYSTEM
Author(s) -
Ye. B. Dmukhalska,
Ya. I. Honsky
Publication year - 2016
Publication title -
medična ì klìnìčna himiâ
Language(s) - English
Resource type - Journals
eISSN - 2414-9934
pISSN - 2410-681X
DOI - 10.11603/mcch.2410-681x.2016.v0.i1.6187
Subject(s) - glutathione , chemistry , antioxidant , enzyme , organophosphate , glutathione reductase , biochemistry , peptide , detoxification (alternative medicine) , pesticide , glutathione peroxidase , biology , agronomy , medicine , alternative medicine , pathology
The reduced glutathione content and the glutathione metabolism enzymes activity in organs and blood plasma of rats under conditions of lead acetate, copper sulphate and glyphosate in Roundup form were studied. The glutathioneperoxidase, the glutathionereductase activity and the concentration of glutathione decreases during action of heavy metals and glyphosate. It was found out that peptide exhibits antioxidant activity, the correction of the peptide and glutathione content.