
Study of acute toxicity and pharmacological activity of dry extract of veronica officinalis
Author(s) -
S. М. Marchyshyn,
Т. Ya. Yaroshenko,
І. І. Мілян,
Sofiia Nakonechna
Publication year - 2015
Publication title -
medična ì klìnìčna himiâ
Language(s) - English
Resource type - Journals
eISSN - 2414-9934
pISSN - 2410-681X
DOI - 10.11603/mcch.2410-681x.2015.v17.i4.5731
Subject(s) - officinalis , diclofenac sodium , toxicity , acute toxicity , traditional medicine , pharmacology , median lethal dose , chemistry , medicine , organic chemistry
The article is devoted to the research of an acute toxicity and anti-inflammatory activity of dry extract of veronica officinalis. It has been found that the studied extract relating to practically non-toxic substances (V class of toxicity according to common classification of toxicity by K. K . S ydorov considering route of administration). According to the results dry extract of veronica officinalis grass under the conditions of caragenin edema showed the most expressive antiexudative activity using 150 mg/kg, slightly behind drug of comparison diclofenac sodium.