Open AccessDynamics of changes in lipid metabolism indices in organs and tissues of experimental animals under adrenaline stress
Author(s) -
S. V. Shkurashivska,
H. M. Ersteniuk
Publication year - 2015
Publication title -
medična ì klìnìčna himiâ
Language(s) - English
Resource type - Journals
eISSN - 2414-9934
pISSN - 2410-681X
DOI - 10.11603/mcch.2410-681x.2015.v17.i4.5681
Subject(s) - endocrinology , medicine , epinephrine , metabolism , chemistry , population , lipid metabolism , blood plasma , cholesterol , biology , environmental health
Diseases of human population, especially in the countries with high level of urbanization, are more often associated now with the influence of different stresses, including emotional one, which is accompanied by adrenaline release. It has been investigated the effect of adrenaline on triacylglycerol (TA G) and cholesterol (CL ) content in different tissues of Wistar rats. It has been determined that under short-term adrenaline load (single injection of adrenaline followed by sample collection after 30 min) TA G level in blood plasma ecreased and simultaneously increased in liver. At the same time CL concentration in blood plasma decreased, while increased in liver and muscles. Double injection of adrenaline followed by sample collection after 30 min caused a decrease in TA G concentration in blood plasma and its increase in liver. Twenty four hours after double adrenaline injection it has been observed decreased TA G and CL levels in blood plasma, whereas it has not differed significantly from control in muscles and liver. Such changes of lipid metabolism under adrenaline stress should be taken into account during evaluation of pathologic process in certain organs.