Open AccessPeculiarities of process es of lipid peroxidation, antioxidant defense and cytolisis in the conditions of an acute gastric ulcer and their correction
Author(s) -
R. I. Tsytsiura
Publication year - 2015
Publication title -
medična ì klìnìčna himiâ
Language(s) - English
Resource type - Journals
eISSN - 2414-9934
pISSN - 2410-681X
DOI - 10.11603/mcch.2410-681x.2015.v17.i3.5065
Subject(s) - lipid peroxidation , antioxidant , chemistry , anabolism , medicine , endocrinology , liver tissue , reflex , biochemistry
Modeling of an acute gastric reflex ulcer is accompanied by lipid peroxidation intensification of processes in the liver tissue (increased content of TBA-active products and diene conjugates) and decrease of antioxidant protection (reduced content ceruloplаzmin serum and total blood peroxide activity). Application on the background of an acute gastric reflex ulcer of Thiotriazoline for seven days at a dose of 9.07 milligram per kilogram of animal intraperitoneally eliminates the found violations and is accompanied by a strong anabolic effect which manifests accumulation of SH-groups in the liver tissue.