Open AccessThe influence of inflammatory complications in patients with acute calculous cholecystitis on the liver functional state
Author(s) -
O. P. Tsymbala,
Л. Е. Лаповец,
В. М. Акімова,
O. I. Martyanova
Publication year - 2015
Publication title -
medična ì klìnìčna himiâ
Language(s) - English
Resource type - Journals
eISSN - 2414-9934
pISSN - 2410-681X
DOI - 10.11603/mcch.2410-681x.2015.v17.i3.5049
Subject(s) - medicine , bilirubin , peritonitis , endogeny , gastroenterology , cholecystitis , albumin , parenchyma , pathology , gallbladder
The urgency of the problems caused by frequent research septic complications in patients with acute calculous cholecystitis (ACC), accompanied by increase of endogenous intoxication. The study involved patients with ACC complicated with choledocholithiasis, acute cholangitis and local peritonitis. The studies found an increase in levels of total serum bilirubin in all groups due to direct fraction, indicating obstructive jaundice. The increase ratio of bilirubin monoglyukuronid/diglucuronide more than 1.0 in septic complications of ACC indicate liver parenchyma lesion and growth of endogenous intoxication. The reduction in serum total protein content by reducing the concentration of albumin in the blood and decrease the reactivity of the organism with the increase of endogenous intoxication in patients with septic complications is observed.