Open AccessChanges of redox reactions in the lung tissue under burn injury and combined application of lyophilized xenographt substrate and exogenous surfactant preparation
Author(s) -
З. М. Небесна,
К. С. Волков,
N Lisnychuk,
І. Ya. Demkiv
Publication year - 2015
Publication title -
medična ì klìnìčna himiâ
Language(s) - English
Resource type - Journals
eISSN - 2414-9934
pISSN - 2410-681X
DOI - 10.11603/mcch.2410-681x.2015.v17.i3.5046
Subject(s) - pulmonary surfactant , antioxidant , chemistry , lipid peroxidation , substrate (aquarium) , oxidative stress , redox , burn injury , pharmacology , biochemistry , medicine , biology , organic chemistry , surgery , ecology
Oxidative stress in the body of the experimental animals after burn injury arises and develops on the background of activation of free radical oxidation and decrease of antioxidant activity and increase of endotoxemia. The combined use of surfactant preparation and lyophilized xenographt substrate after skin burns lead to a significant decrease of endotoxemia, inhibition of lipid peroxidation processes and restoring functional activity of antioxidant protection.