Open AccessHypersensitivity to Ibuprofen: Real-Life Experience in Children with History of Suspected Immediate Reactions
Author(s) -
Sevgi Sipahi Çimen,
Esra Yücel,
Ayşe Süleyman,
Zeynep Hızlı Demirkale,
Deniz Özçeker,
Uğurcan Sayılı,
Nermin Güler,
Zeynep Tamay
Publication year - 2022
Publication title -
international archives of allergy and immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.696
H-Index - 100
eISSN - 1423-0097
pISSN - 1018-2438
DOI - 10.1159/000526981
Subject(s) - ibuprofen , medicine , angioedema , culprit , allergy , provocation test , drug allergy , anaphylaxis , drug , dermatology , nimesulide , hypersensitivity reaction , pediatrics , immunology , pharmacology , pathology , alternative medicine , myocardial infarction
Ibuprofen is the most common culprit drug causing nonsteroidal anti-inflammatory drug (NSAID) hypersensitivity in children. We aimed to evaluate the frequency, clinical characteristics, and risk factors of confirmed ibuprofen allergy in children presenting with a history of suspected immediate type ibuprofen-induced hypersensitivity reactions.