Open AccessThe Development of Pulmonary Edema after Recombinant Tissue Plasminogen Activator in Acute Ischemic Stroke Patient; Neurogenic or Non-Neurogenic?
Author(s) -
Ahmad Sulaiman Alwahdy,
Ika Yulieta Margaretha Sihombing,
Fitria Tahta Alfina,
Niken Syahdian,
Putri Nurbaeti,
Annisa Futihandayani,
Allifka Ramadhanti
Publication year - 2022
Publication title -
case reports in neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.207
H-Index - 15
ISSN - 1662-680X
DOI - 10.1159/000526250
Subject(s) - medicine , recombinant tissue plasminogen activator , thrombolysis , stroke (engine) , tissue plasminogen activator , pulmonary edema , edema , pathophysiology , cerebral edema , etiology , cardiology , anesthesia , ischemia , lung , ischemic stroke , myocardial infarction , mechanical engineering , modified rankin scale , engineering
Recombinant tissue plasminogen activator (r-tPA) is the first-line drug for the treatment of acute ischemic stroke, despite it may lead to a variety of complications in some cases. In patients with extensive stroke, infarction of the brain can cause suppression of the respiratory center in the brain leading to neurogenic pulmonary edema that potentially causes respiratory failure. Its etiology is either due to a neurogenic or non-neurogenic process. Nevertheless, the definite pathophysiology of these circumstances remains unclear. In this study, we reported four cases of post-thrombolytic ischemic stroke patients who suffer from pulmonary edema with different symptoms and onset times as well as we discuss the possible explanation behind these different outcomes.