Open AccessStatin Therapy for Preventing Recurrent Stroke in Patients with Ischemic Stroke: A Systematic Review and Meta-Analysis of Randomized Controlled Trials and Observational Cohort Studies
Author(s) -
Yuyao Yin,
Li Zhang,
Iain Marshall,
Charles Wolfe,
Yanzhong Wang
Publication year - 2022
Publication title -
neuroepidemiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.217
H-Index - 87
eISSN - 1423-0208
pISSN - 0251-5350
DOI - 10.1159/000525672
Subject(s) - medicine , observational study , stroke (engine) , randomized controlled trial , statin , cohort , meta analysis , cohort study , odds ratio , physical therapy , mechanical engineering , engineering
Statins are effective in preventing vascular disease and are widely recommended and used for the secondary prevention of ischemic stroke. However, there is concern from trials that statins might increase the risk of hemorrhagic stroke, partially reducing their benefit. We sought to systematically review the latest evidence on this question.