Open AccessEndotoxemic Shock: A Molecular Phenotype in Sepsis
Author(s) -
John A. Kellum,
Debra Foster,
Paul Walker
Publication year - 2022
Publication title -
the nephron journals/nephron journals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.951
H-Index - 72
eISSN - 2235-3186
pISSN - 1660-8151
DOI - 10.1159/000525548
Subject(s) - sepsis , medicine , organ dysfunction , phenotype , shock (circulatory) , septic shock , acute kidney injury , inflammation , narrative review , immunology , clinical phenotype , intensive care medicine , bioinformatics , gene , biology , genetics
Marked heterogeneity exists among patients with sepsis, both in terms of distribution of organ dysfunction and its severity. Such heterogeneity could be explained by the presence of multiple subtypes of sepsis that may have important implications for treatment.