Open AccessRecent Advances in Immune-Based Therapies for Type 1 Diabetes
Author(s) -
Darja Šmigoc Schweiger
Publication year - 2022
Publication title -
hormone research in paediatrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.816
H-Index - 89
eISSN - 1663-2826
pISSN - 1663-2818
DOI - 10.1159/000524866
Subject(s) - medicine , disease , immune system , immunotherapy , immunology , autoimmunity , diabetes mellitus , clinical trial , t cell , type 2 diabetes , pathogenesis , bioinformatics , endocrinology , biology
Type 1 diabetes (T1D) is a chronic autoimmune disease characterized by progressive destruction of the pancreatic beta cells, leading to a lifelong dependence on insulin. It is associated with an increased morbidity and mortality from diabetes-related complications and a significant treatment burden. However, there has been substantial progress in therapeutic strategies that can affect the course of the disease.