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Epiretinal Membrane in Patients with Diabetic Macular Edema
Author(s) -
Gilad Rabina,
Assaf Hilely,
Dana Barequet,
Shai Cohen,
Naama Lipin,
Michael Mimouni,
Adina Glick,
Adiel Barak,
Anat Loewenstein,
Shulamit Schwartz
Publication year - 2022
Publication title -
ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.639
H-Index - 60
eISSN - 1423-0267
pISSN - 0030-3755
DOI - 10.1159/000524742
Subject(s) - medicine , epiretinal membrane , diabetic retinopathy , vitrectomy , ophthalmology , pars plana , diabetic macular edema , visual acuity , macular edema , diabetes mellitus , retrospective cohort study , surgery , endocrinology
PURPOSE: To compare anatomical and functional outcomes of pars plana vitrectomy (PPV) with epiretinal membrane (ERM) peeling in diabetes retinopathy (DR) patients with and without diabetic macular edema (DME).METHODS: A retrospective interventional case series of consecutive patients who underwent PPV with ERM peeling. Patients were divided into two groups: With and without preoperative DME. Visual acuity (VA) and optical coherence tomography (OCT) parameters were evaluated before surgery and during 12 months follow-up. RESULTS: A total of 354 patients underwent PPV with ERM peeling, of which 51 met the inclusion criteria. Twenty-three were diagnosed with DME and were younger (66.3±9.6 vs 73.1±8.2years, p=0.001), had longer diabetes mellitus (DM) duration (18.9±7.1 vs 14.3±10.9 years, p=0.04) and higher HbA1C% (7.6±1.4 vs. 7.1±1.3, p=0.04). VA improved from 20/105 to 20/60 Snellen (p=0.004) and central macular thickness (CMT) decreased from 469.3±64.9μm to 331.1±92.2μm (p<0.001) in the DME group and from 20/87 to 20/44 Snellen (p<0.001) and from 463.1±53.5μm to 341.3±49.5 μm (p=0.01) in the non DME group. Yearly intravitreal injections rate decreased from 5.9±2.5 to 2.9±3.0 (p<0.001) injections in the DME group.CONCLUSIONS: DME patients with ERM, experience significant improvement in VA, macular thickness and yearly intravitreal injections after PPV with ERM peeling. DME patients are younger, with longer duration of DM and higher HbA1C% levels at presentation in comparison to diabetic ERM patients without DME.

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