Open AccessAdvances in the Pharmacological Intervention of Endothelial Progenitor Cells in the Treatment of Ischemic Stroke
Author(s) -
Lu Lu,
Jiajie Zhu,
Haiyan Zhang,
Xiaoping Li,
Keda Chen
Publication year - 2022
Publication title -
cerebrovascular diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.221
H-Index - 104
eISSN - 1421-9786
pISSN - 1015-9770
DOI - 10.1159/000524414
Subject(s) - medicine , stroke (engine) , progenitor cell , ischemic stroke , intervention (counseling) , endothelial progenitor cell , cardiology , ischemia , intensive care medicine , stem cell , psychiatry , biology , mechanical engineering , genetics , engineering
Ischemic stroke, a common central nervous system disease that seriously threatens human life and health, is characterized by rapid progress and a high disability fatality rate. Ischemic tissue can produce a large amount of vascular endothelial growth factor (VEGF) and stromal cell-derived factor 1 (SDF-1) to promote the mobilization of endothelial progenitor cells (EPCs).