Open AccessIntraocular Lens and Lens Capsule Spread of Iridociliary Melanoma: Clinical and Histopathologic Features of 2 Cases
Author(s) -
Corrina P. Azarcon,
Jill R. Wells,
Thomas M. Aaberg,
Hans E. Grossniklaus
Publication year - 2022
Publication title -
ocular oncology and pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.444
H-Index - 10
eISSN - 2296-4681
pISSN - 2296-4657
DOI - 10.1159/000524052
Subject(s) - medicine , enucleation , capsule , melanoma , ciliary body , ophthalmology , intraocular lens , brachytherapy , lens (geology) , surgery , radiation therapy , cancer research , optics , botany , biology , physics
Purpose: To describe two patients with intraocular lens (IOL) and lens capsule spread of iridociliary melanoma.Methods: Two pseudophakic patients with iridociliary body melanoma that spread onto the surface of their IOL and remaining lens capsule were included. Their eyes were enucleated and the histopathologic features were evaluated.Results: Case 1 was an 82-year-old woman with diffuse primary iridociliary melanoma affecting the iris, lens capsule, IOL surface, and ciliary body. Case 2 was a 68-year-old female who developed melanoma recurrence in the anterior segment after plaque brachytherapy for iridociliary melanoma. The melanoma in both cases grew as a pigmented membrane onto the surface of the IOL.Conclusions: Intraocular lens and lens capsule spread of iridociliary melanoma can occur primarily or develop secondarily after plaque brachytherapy of a pseudophakic eye. Since the extent of the melanoma may be uncertain and there is a high likelihood of glaucoma, enucleation is a reasonable option.