Open AccessNeonatal Cerebral Venous Thrombosis following Maternal SARS-CoV-2 Infection in Pregnancy
Author(s) -
Francesca Campi,
Daniela Longo,
Iliana Bersani,
Immacolata Savarese,
G. Lucignani,
Cristina Haass,
Maria Chiara Paolino,
Sarah Vadalà,
Paola De Liso,
M. Di Capua,
Matteo Luciani,
Giacomo Esposito,
Paolina Giuseppina Amante,
Federico Vigevano,
Andrea Dotta
Publication year - 2022
Publication title -
neonatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.399
H-Index - 84
eISSN - 1661-7819
pISSN - 1661-7800
DOI - 10.1159/000520537
Subject(s) - medicine , complication , pregnancy , venous thrombosis , thrombosis , pathophysiology , coagulopathy , pediatrics , genetics , biology
A possible consequence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is the development of an exacerbated thrombophilic status, and cerebral venous thrombosis (CVT) is a rare but possible complication of SARS-CoV-2 infection reported both in adults and in children. The present case report describes the clinical course of a term neonate showing extended CVT of unclear origin, whose mother had developed SARS-CoV-2 infection during the third trimester of pregnancy. We speculate that the prothrombotic status induced by maternal SARS-CoV-2 infection may have played a pathophysiological role in the development of such severe neonatal complication. Further investigations are required to confirm such hypothesis.